Trends in Cardiovascular Medicine
Volume 15, Issue 4 , Pages 125-129, May 2005

Transcriptional Regulation at the Chromatin Level in the Cardiovasculature Through Protein-protein Interactions and Chemical Modifications

  • Toru Suzuki

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Toru Suzuki, MD, PhD, Department of Cardiovascular Medicine, Department of Clinical Bioinformatics, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Tel.: (+81) 3-3815-5411 ext. 33117; fax: (+81) 3-5800-8824.
  • ,
  • Takayoshi Matsumura
  • ,
  • Ryozo Nagai

Transcriptional regulation in eukaryotes requires an understanding of the regulation of the chromatin structure. Chromatin is the eukaryotic-specific packaging/compaction of DNA with nucleosomal histones. This present review discusses recent advancements made in the field of chromatin-associated transcriptional regulation and their implications to the cardiovasculature.

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PII: S1050-1738(05)00030-7

doi:10.1016/j.tcm.2005.04.003

Trends in Cardiovascular Medicine
Volume 15, Issue 4 , Pages 125-129, May 2005