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Trends in Cardiovascular Medicine
Volume 16, Issue 1
, Pages 7-15
, January 2006
ATP-Binding Cassette Transporters in the Heart
References
- Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science. 1995;268:423–426
- . Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2). Mol Cancer Ther. 2002;1:427–434
- . Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. Hum Mol Genet. 1996;5:1649–1655
- . Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes. Mamm Genome. 2003;14:7–20
- . Reconstituted human cardiac KATP channels: functional identity with the native channels from the sarcolemma of human ventricular cells. Circ Res. 1998;83:1132–1143
- Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins. J Natl Cancer Inst. 1998;90:1735–1741
- ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating. Nat Genet. 2004;36:382–387
- . Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels. Diabetes. 1996;45:1439–1445
- Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood–brain barrier sites. Proc Natl Acad Sci U S A. 1989;86:695–698
- . Investigation of the influence of modulation of P-glycoprotein by a multiple dosing regimen of tamoxifen on the pharmacokinetics and toxicodynamics of doxorubicin. Cancer Chemother Pharmacol. 2005;56:497–509
- Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart. Am J Pathol. 2003;163:1567–1577
- . The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem Biophys Res Commun. 1992;189:551–557
- Prescribing digoxin in geriatric units: the unexplained variability in dosage requirements. Eur J Clin Pharmacol. 1987;32:611–614
- . Quinidine-digoxin interaction: pharmacokinetics, underlying mechanism and clinical implications. N Engl J Med. 1979;301:400–404
- . Effect of PSC 833, verapamil and amiodarone on adriamycin toxicity in cultured rat cardiomyocytes. Toxicol In Vitro. 2000;14:17–23
- . Importance of P-glycoprotein at blood–tissue barriers. Trends Pharmacol Sci. 2004;25:423–429
- Inhibition of P-glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine. Circulation. 1999;99:552–557
- . Metabolic cardiomyopathies. Int J Exp Pathol. 2000;81:349–372
- . The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation. Curr Drug Metab. 2004;5:21–53
- . The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem. 2000;275:30069–30074
- Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages. Biochem Biophys Res Commun. 2001;281:249–258
- ABCA6, a novel a subclass ABC transporter. Biochem Biophys Res Commun. 2001;285:1295–1301
- . Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein. Br J Pharmacol. 1993;110:1009–1016
- . An inventory of the human ABC proteins. Biochim Biophys Acta. 1999;1461:237–262
- Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim Biophys Acta. 1999;1461:377–394
- ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms. Mol Cell Biol. 2005;25:4138–4149
- Cardiomyocytes of chronically ischemic pig hearts express the MDR-1 gene-encoded P-glycoprotein. J Histochem Cytochem. 2005;53:845–850
- Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res. 2001;61:3458–3464
- Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy. J Histochem Cytochem. 2002;50:1351–1356
- Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms. Pharmacogenetics. 2004;14:381–385
- The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart217. J Histochem Cytochem. 2005;(in press)
- . Expression of multidrug resistance protein 4 and 5 in the porcine coronary and pulmonary arteries. Eur J Pharmacol. 2003;466:223–224
- . SUR, ABC proteins targeted by K(ATP) channel openers. J Mol Cell Cardiol. 2005;38:951–963
- Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. BMC Physiol. 2005;5:1
- Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature. 2000;406:906–910
- . ATP-regulated K+ channels in cardiac muscle. Nature. 1983;305:147–148
- . Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant. Biochem Biophys Res Commun. 2003;300:343–350
- Subcellular localisation of rAbca5, a rat ATP-binding cassette transporter expressed in Leydig cells, and characterisation of its splice variant apparently encoding a half-transporter. Biochem J. 2005;(in press)
- . Extracellular 3′,5′ cyclic guanosine monophosphate inhibits kainate-activated responses in cultured mouse cerebellar neurons. J Pharmacol Exp Ther. 1998;286:99–109
- . Digoxin–quinidine interaction. Johns Hopkins Med J. 1979;145:227–229
- . ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes. Genomics. 1998;53:137–145
- Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5). Drug Metab Rev. 2005;37:253–278
- Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state. J Biol Chem. 2005;280:2857–2862
- Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Genomics. 1997;41:275–278
- Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest. 1995;96:1698–1705
- Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc Natl Acad Sci U S A. 1997;94:4028–4033
- . Genetic polymorphisms of the human MDR1 drug transporter. Annu Rev Pharmacol Toxicol. 2003;43:285–307
- . Function and distribution of the SUR isoforms and splice variants. J Mol Cell Cardiol. 2005;39:51–60
- Effects of verapamil on the acute toxicity of doxorubicin in vivo. J Natl Cancer Inst. 1992;84:1653–1660
- Functional analysis of ABCA8, a new drug transporter. Biochem Biophys Res Commun. 2002;298:41–45
- . ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner. J Biol Chem. 2000;275:34131–34139
- . Expression of a full-length cDNA for the human “MDR1” gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc Natl Acad Sci U S A. 1987;84:3004–3008
- Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein. Br J Cancer. 1999;79:108–113
- Cloning and characterization of human adenosine 5′-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2). Cancer Res. 2001;61:3339–3347
- ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter. Biochem Biophys Res Commun. 2003;306:1089–1098
- Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction. Clin Pharmacol Ther. 2000;68:345–355
- Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes. J Biol Chem. 2000;275:23287–23294
PII: S1050-1738(05)00186-6
doi: 10.1016/j.tcm.2005.10.001
© 2006 Elsevier Inc. All rights reserved.
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Trends in Cardiovascular Medicine
Volume 16, Issue 1
, Pages 7-15
, January 2006
