Trends in Cardiovascular Medicine
Volume 16, Issue 2 , Pages 38-45 , February 2006

Vang-like 2 and Noncanonical Wnt Signaling In Outflow Tract Development

  • Deborah J. Henderson

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Deborah Henderson, Institute of Human Genetics, University of Newcastle upon Tyne, International Centre for Life, NE1 3BZ Newcastle upon Tyne, UK. Tel.: (+44) 191-241-8644; fax: (+44) 191-241-8666.
    • ,
  • Helen M. Phillips
    • ,
  • Bill Chaudhry

References 

  1. Bamforth SD, Braganca J, Farthing CR, et al. Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Nat Genet. 2004;36:1189–1196
  2. Curtin JA, Quint E, Tsipouri V, et al. Mutation of Celsr1 disrupts planar polarity of inner ear cells and causes severe neural tube defects in the mouse. Curr Biol. 2003;13:1129–1133
  3. Darken RS, Scola AM, Rakeman AS, et al. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J. 2002;21:976–985
  4. De Calisto J, Araya C, Marchant L, et al. Essential role of noncanonical Wnt signalling in neural crest migration. Development. 2005;132:2587–2597
  5. Edmonds LD, James LM. Temporal trends in the birth prevalence of selected congenital malformations in the Birth Defects Monitoring Program/Commission on Professional and Hospital Activities, 1979-1989. Teratology. 1993;48:647–649
  6. Garriock RJ, D'Agostino SL, Pilcher KC, Krieg PA. Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in Xenopus. Dev Biol. 2005;279:179–192
  7. Goto T, Keller R. The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus. Dev Biol. 2002;247:165–181
  8. Greene NDE, Gerrelli D, Van Straaten HWM, Copp AJ. Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: A model of severe neural tube defects. Mech Dev. 1998;73:59–72
  9. Hamblet NS, Lijam N, Ruiz-Lozano P, et al. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development. 2002;129:5827–5838
  10. Heisenberg CP, Tada M, Rauch GJ, et al. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature. 2000;405:76–81
  11. Henderson DJ, Conway SJ, Greene ND, et al. Cardiovascular defects associated with abnormalities in midline development in the loop-tail mouse mutant. Circ Res. 2001;89:6–12
  12. Hutson MR, Kirby ML. Neural crest and cardiovascular development: A 20-year perspective. Birth Defects Res C Embryo Today. 2003;69:2–13
  13. Kaarbo M, Crane DI, Murrell WG. RhoA is highly upregulated in the process of early heart development of the chick and important for normal embryogenesis. Dev Dyn. 2003;227:35–47
  14. Kaartinen V, Dudas M, Nagy A, et al. Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells. Development. 2004;131:3481–3490
  15. Katz SG, Williams A, Yang J, et al. Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development. Proc Natl Acad Sci U S A. 2003;100:14030–14035
  16. Keller R. Shaping the vertebrate body plan by polarized embryonic cell movements. Science. 2002;298:1950–1954
  17. Kelly RG, Brown NA, Buckingham ME. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev Cell. 2001;1:435–440
  18. Kibar Z, Vogan KJ, Groulx N, et al. Ltap, a mammalian homolog of Drosophila strabismus/Van Gogh, is altered in the mouse neural tube mutant loop-tail. Nat Genet. 2001;28:251–255
  19. Kirby ML, Gale TF, Stewart DE. Neural crest cells contribute to normal aorticopulmonary septation. Science. 1983;220:1059–1061
  20. Klein TJ, Mlodzik M. Planar cell polarization: An emerging model points in the right direction. Annu Rev Cell Dev Biol. 2005;21:155–176
  21. Kohn AD, Moon RT. Wnt and calcium signaling: Beta-catenin-independent pathways. Cell Calcium. 2005;38:439–446
  22. Kruithof BP, van den Hoff MJ, Wessels A, Moorman AF. Cardiac muscle cell formation after development of the linear heart tube. Dev Dyn. 2003;227:1–13
  23. Kruithof BPT, van den Hoff MJB, Tesink-Taekema S, Moorman AFM. Recruitment if intra- and extracardiac cells into the myocardial lineage during mouse development. Anat Rec Part A. 2003;271A:303–314
  24. Lawrence N, Morel V. Dorsal closure and convergent extension: Two polarised morphogenetic movements controlled by similar mechanisms?. Mech Dev. 2003;120:1385–1393
  25. Manner J, Seidl W, Steding G. Correlation between the embryonic head flexures and cardiac development. An experimental study in chick embryos. Anat Embryol (Berl). 1993;188:269–285
  26. Mjaatvedt CH, Nakaoka T, Moreno-Rodriguez R, et al. The outflow tract of the heart is recruited from a novel heart-forming field. Dev Biol. 2001;238:97–109
  27. Montcouquiol M, Rachel RA, Lanford PJ, et al. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature. 2003;423:173–177
  28. Murdoch JN, Doudney K, Paternotte C, et al. Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum Mol Genet. 2001;10:2593–2601
  29. Phillips HM, Murdoch JN, Chaudhry B, et al. Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract. Circ Res. 2005;96:292–299
  30. Riento K, Ridley AJ. Rocks: Multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol. 2003;4:446–456
  31. Ross AJ, May-Simera H, Eichers ER, et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet. 2005;37:1135–1140
  32. Shaw GM, O'Maley CD, Wasserman CR, et al. Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring. Am J Med Genet. 1995;59:536–545
  33. Smith LJ, Stein KF. Axial elongation in the mouse and its retardation in homozygous looptail mice. J Embryol Exp Morph. 1962;10:73–87
  34. Strong LC, Hollander WF. Hereditary loop-tail in the house mouse. J Hered. 1949;40:329–334
  35. Strutt D. Frizzled signaling and cell polarization in Drosophila and vertebrates. Development. 2003;130:4501–4513
  36. Tullio AN, Accili D, Ferrans VJ, et al. Nonmuscle myosin II-B is required for normal development of the mouse heart. Proc Natl Acad Sci U S A. 1997;94:12407–12412
  37. Waldo KL, Kumiski DH, Wallis KT, et al. Conotruncal myocardium arises from a secondary heart field. Development. 2001;128:3179–3188
  38. Wang J, Mark S, Zhang X, et al. Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet. 2005;37:980–985
  39. Ward C, Stadt H, Hutson M, Kirby ML. Ablation of the secondary heart field leads to tetralogy of Fallot and pulmonary atresia. Dev Biol. 2005;284:72–83
  40. Wei L, Roberts W, Wang L, et al. Rho kinases play an obligatory role in vertebrate organogenesis. Development. 2001;128:2953–2962

PII: S1050-1738(05)00219-7

doi: 10.1016/j.tcm.2005.11.005

Trends in Cardiovascular Medicine
Volume 16, Issue 2 , Pages 38-45 , February 2006

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