Trends in Cardiovascular Medicine
Volume 16, Issue 3 , Pages 95-101 , April 2006

Blood-Forming Endothelium in Human Ontogeny: Lessons From In Utero Development and Embryonic Stem Cell Culture

References 

  1. Bloom W, Bartelmez GW. Hematopoiesis in young human embryos. Am J Anat. 1940;67:21–53
  2. Bollerot K, Romero S, Dunon D, Jaffredo T. Core binding factor in the early avian embryo: cloning of cbfbeta and combinational expression patterns with Runx-1. Gene Expr Patterns. 2005;6(1):29–39
  3. Brown LA, Rodaway AR, Schilling TF, et al. Insight into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mech Dev. 2000;90:237–252
  4. Choi K, Kennedy M, Kazarov A, et al. A common precursor for hematopoietic and endothelial cells. Development. 1998;125:725–732
  5. Ciau-Uitz A, Walmsley M, Patient R. Distinct origins of adult and embryonic blood in Xenopus. Cell. 2000;102:787–796
  6. Cortes F, Debacker C, Péault B, Labastie MC. Differential expression of KDR/VEGFR-2 and CD34 during mesoderm development of the early human embryo. Mech Dev. 1999;83:161–164
  7. Davidson AJ, Ernst P, Wang Y, et al. cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature. 2003;425:300–306
  8. Dzierzak E. Ontogenic emergence of definitive hematopoietic stem cells. Curr Opin Hematol. 2003;10:229
  9. Gering M, Patient R. Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos. Dev Cell. 2005;8:389–400
  10. Godin I, Cumano A. Of birds and mice: hematopoietic stem cell development. Int J Dev Biol. 2005;49:251–257
  11. Gunsilius E, Duba HC, Petzer AL, et al. Evidence from a leukaemia model for maintenance of vascular endothelium by bone-marrow-derived endothelial cells. Lancet. 2000;355:1688–1691
  12. Huber TL, Kouskoff V, Fehling HJ, et al. Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature. 2004;432:625–630
  13. Jaffredo T, Gautier R, Eichmann A, Dieterlen-Lievre F. Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development. 1998;125:4575–4583
  14. Kabrun N, Buhring HJ, Choi K, et al. Flk-1 expression defines a population of early embryonic hematopoietic precursors. Development. 1997;124:2039–2048
  15. Keller G, Kennedy M, Papayannopoulou T, Wiles MV. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol. 1993;13:473–486
  16. Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell. 2002;109:29–37
  17. Kyba M, Perlingeiro RC, Hoover RR, et al. Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5. Proc Natl Acad Sci U S A. 2003;100:11904–11910
  18. Labastie MC, Cortés F, Roméo PH, et al. Molecular identity of hematopoietic precursor cells emerging in the human embryo. Blood. 1998;92:3624–3635
  19. Le Douarin NM, Houssaint E, Jotereau FV, Belo M. Origin of hemopoietic stem cells in embryonic bursa of Fabricius and bone marrow studied through interspecific chimeras. Proc Natl Acad Sci U S A. 1975;72:2701–2705
  20. McGrath K, Palis J. Hematopoiesis in the yolk sac: more than meets the eye. Exp Hematol. 2005;33:1021–1028
  21. Murray PDF. The development ‘invitro’ of blood of the early chick embryo. Proc Roy Soc London. 1932;11:497–521
  22. Nishikawa SI, Nishikawa S, Kawamoto H, et al. In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Immunity. 1998;8:761–769
  23. North TE, de Bruijn MF, Stacy T, et al. Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity. 2002;16:661–672
  24. Oberlin E, Tavian M, Blazsek I, Péault B. Blood-forming potential of vascular endothelium in the human embryo. Development. 2002;129:4147–4457
  25. Palis J, Robertsin S, Kennedy M, et al. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development. 1999;126:5073–5084
  26. Porcher C, Swat W, Rockwell K, et al. The T cell leukemia oncoprotein SCL/tal1 is essential for development of all hematopoietic lineages. Cell. 1996;86:47–57
  27. Robertson SM, Kennedy M, Shannon JM, Keller G. A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1. Development. 2000;127:2447–2459
  28. Sabin FR. Studies on the origin of blood vessels and of red blood corpuscles as seen in the living blastoderm of checks during the second day of incubation. In: Contrib Embryol. 9:Carnegie Institute Washington; 1920;p. 214;[Pub. no. 272]
  29. Tavian M, Péault B. Embryonic development of the human hematopoietic system. Int J Dev Biol. 2005;49:243–250
  30. Tavian M, Coulombel L, Luton D, et al. Aorta-associated CD34+ hematopoietic cells in the early human embryo. Blood. 1996;87:67–72
  31. Tavian M, Hallais MF, Péault B. Emergence of intraembryonic hematopoietic precursors in the pre-liver human embryo. Development. 1999;126:793–803
  32. Tavian M, Robin C, Coulombel L, Péault B. The human embryo, but not its yolk sac, generates lympho-myeloid stem cells. mapping multipotent hematopoietic cell fate in intraembryonic mesoderm. Immunity. 2001;15:487–495
  33. Tavian M, Zheng B, Oberlin E, et al. The vascular wall as a source of stem cells. Ann N Y Acad Sci. 2005;1044:41–50
  34. Vittet D, Prandini MH, Berthier R, et al. Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood. 1996;88(9):3424–3431
  35. Wang L, Li L, Shojaei F, et al. Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity. 2004;20:31–41
  36. Wang Y, Yates F, Naveiras O, et al. Embryonic stem cell-derived hematopoietic stem cells. Proc Natl Acad Sci. 2005;102:19081–19086
  37. Wiles MV, Keller G. Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture. Development. 1991;111:259–267
  38. Zambidis ET, Péault B, Park TS, et al. Hematopoietic differentiation of human embryonic stem cells progresses through sequential hemato-endothelial, primitive, and definitive stages resembling human yolk sac development. Blood. 2005;106:860–870

PII: S1050-1738(06)00018-1

doi: 10.1016/j.tcm.2006.01.005

Trends in Cardiovascular Medicine
Volume 16, Issue 3 , Pages 95-101 , April 2006