Trends in Cardiovascular Medicine
Volume 16, Issue 4 , Pages 128-139, May 2006

Are Intra-Aortic Hemopoietic Cells Derived from Endothelial Cells During Ontogeny?

  • Françoise Dieterlen-Lièvre

      Affiliations

    • UMR 7128 Laboratoire d'Embryologie Cellulaire et Moléculaire, 94130 Nogent-sur-Marne, France
    • Corresponding Author InformationAddress correspondence to: Françoise Dieterlen-Lièvre and Thierry Jaffredo, UMR 7622 Laboratoire de Biologie du Développement, 75252 Paris Cedex 05, France.
    • Present address: IAF, UPR2197, 91198 Gif sur Yvette, France.
    • ,
  • Claire Pouget

      Affiliations

    • UPMC, CNRS UMR7622, Laboratoire de Biologie du Développement, 75252 Paris Cedex 05, France
    • ,
  • Karine Bollérot

      Affiliations

    • UPMC, CNRS UMR7622, Laboratoire de Biologie du Développement, 75252 Paris Cedex 05, France
    • ,
  • Thierry Jaffredo

      Affiliations

    • UMR 7128 Laboratoire d'Embryologie Cellulaire et Moléculaire, 94130 Nogent-sur-Marne, France
    • UPMC, CNRS UMR7622, Laboratoire de Biologie du Développement, 75252 Paris Cedex 05, France
    • Corresponding Author InformationAddress correspondence to: Françoise Dieterlen-Lièvre and Thierry Jaffredo, UMR 7622 Laboratoire de Biologie du Développement, 75252 Paris Cedex 05, France.

The aorta is recognized as an intraembryonic site that produces adult-type hemopoietic stem cells. A corpus of data indicates that hemopoietic cells arranged as clusters attached to the aortic floor derive from an endothelial intermediate. This review reports on experimental approaches carried out in the avian embryo to establish the developmental history of the aortic endothelium and trace the origin of associated hemopoietic cells.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1050-1738(06)00042-9

doi:10.1016/j.tcm.2006.02.005

Trends in Cardiovascular Medicine
Volume 16, Issue 4 , Pages 128-139, May 2006

Article Tools

* Image Usage & Resolution