Trends in Cardiovascular Medicine
Volume 16, Issue 5 , Pages 153-156, July 2006

Blood Vessels Engineered from Human Cells

Department of Anesthesia, Duke University, Durham, NC 27708, USA

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA

Human vascular tissue engineering has progressed substantially over the past decade. Issues remain as to the optimum culture scaffold and cell source that should be used for arterial regeneration. In addition, limitations in replicative life span of adult human cells as compared with young animal cells have made human vascular tissue engineering more challenging. Despite these obstacles, several strategies for generating replacement vessels have progressed to clinical trials.

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PII: S1050-1738(06)00045-4

doi:10.1016/j.tcm.2006.02.006

Trends in Cardiovascular Medicine
Volume 16, Issue 5 , Pages 153-156, July 2006

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