Trends in Cardiovascular Medicine
Volume 18, Issue 4 , Pages 117-125, May 2008

Percutaneous Heart Valve Replacement: An Update

  • Hossein Ghanbari

      Affiliations

    • Academic Division of Surgical and Interventional Sciences, University College London, London NW3 2PF, UK
    • Cardiovascular Haemodynamic Centre, University College London, London NW3 2PF, UK
  • ,
  • Asmeret G. Kidane

      Affiliations

    • Academic Division of Surgical and Interventional Sciences, University College London, London NW3 2PF, UK
  • ,
  • Gaetano Burriesci

      Affiliations

    • Department of Mechanical Engineering, University College London, London WC1E 7JE, UK
  • ,
  • Philipp Bonhoeffer

      Affiliations

    • Cardiothoracic Unit, Institute of Child Health and Great Ormond Street Hospital for Children, London WC1N 3JH, UK
  • ,
  • Alexander M. Seifalian

      Affiliations

    • Academic Division of Surgical and Interventional Sciences, University College London, London NW3 2PF, UK
    • Cardiovascular Haemodynamic Centre, University College London, London NW3 2PF, UK
    • Corresponding Author InformationAddress correspondence to: Professor Alexander M. Seifalian, Academic Division of Surgical and, Interventional Sciences, University College London, Rowland Hill Street, London NW3 2PF, UK. Tel.: (+44) 20 7830 2901

Valvular heart disease continues to be an important health care problem. Although surgical valve replacement remains the standard treatment, minimally invasive approaches for valve repair and replacement are becoming attractive alternatives among physicians and patients. In fact, percutaneous procedures can extend treatment to the increasing population of elderly patients with severe comorbidities who cannot withstand the stress of open heart surgery and to the younger patients at the early stage of valve disease, who are not treated until older ages to avoid multiple invasive surgeries. Feasibility of this technique has been shown in the first clinical experiences, and the early results are promising. However, it is clear that percutaneous valve replacement therapy is still at the early stage of development and requires enhanced implantation procedures and substantial design improvements as well as long-term follow-up to show the safety and effectiveness of this new treatment modality.

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PII: S1050-1738(08)00029-7

doi:10.1016/j.tcm.2008.02.002

Trends in Cardiovascular Medicine
Volume 18, Issue 4 , Pages 117-125, May 2008