Trends in Cardiovascular Medicine
Volume 18, Issue 4 , Pages 126-133, May 2008

Beyond Receptor Expression Levels: The Relevance of Target Accessibility in Ligand-Directed Pharmacodelivery Systems

  • Michael G. Ozawa

      Affiliations

    • Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Amado J. Zurita

      Affiliations

    • Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Emmanuel Dias-Neto

      Affiliations

    • Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Diana N. Nunes

      Affiliations

    • Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Richard L. Sidman

      Affiliations

    • Harvard Medical School and Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, MA 02115, USA
    • ,
  • Juri G. Gelovani

      Affiliations

    • Department of Experimental Diagnostic Imaging, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Wadih Arap

      Affiliations

    • Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • Corresponding Author InformationAddress correspondence to: Renata Pasqualini or Wadih Arap, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Tel.: (+1) 713 792 3873; fax: (+1) 713 745 2999
    • These authors contributed equally to this work.
    • ,
  • Renata Pasqualini

      Affiliations

    • Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • Corresponding Author InformationAddress correspondence to: Renata Pasqualini or Wadih Arap, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Tel.: (+1) 713 792 3873; fax: (+1) 713 745 2999
    • These authors contributed equally to this work.

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PII: S1050-1738(08)00043-1

doi:10.1016/j.tcm.2008.03.001

Trends in Cardiovascular Medicine
Volume 18, Issue 4 , Pages 126-133, May 2008

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